Actualités
Publications de nos équipes - avril 2012
Long-Term Analysis of the IFM 99 Trials for Myeloma : Cytogenetic Abnormalities [t(4 ;14), del(17p), 1q gains] Play...Publié le 10-05-2012
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Publications de nos équipes - Mars 2012
p27Kip1 controls cytokinesis via the regulation of citron kinase activation. Serres MP, Kossatz U, Chi Y, Roberts...Publié le 03-04-2012
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Pole de recherche hospitalo-universitaire CAPTOR
Le projet CAPTOR (Cancer Pharmacology of Toulouse and Region ) a été labellisé par l’ANR , dans le cadre des...Publié le 22-03-2012
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Publications de nos équipes - Février 2012
Size control of the Drosophila hematopoietic niche by bone morphogenetic protein signaling reveals parallels with...Publié le 05-03-2012
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Labex Toucan
Le projet Toucan a été labellisé dans le cadre de l’appel d’offre Labex (Laboratoire d’excellence). Félicitations au...Publié le 22-02-2012
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Les équipes > Actualités équipes
Publications de nos équipes- juillet 2010
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.
Lemée F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roché H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C. Proc Natl Acad Sci U S A. 2010 Jul 27 ;107(30):13390-5.
Lemée F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roché H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C. Proc Natl Acad Sci U S A. 2010 Jul 27 ;107(30):13390-5.
Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands.
de Medina P, Paillasse MR, Segala G, Poirot M, Silvente-Poirot S. Proc Natl Acad Sci U S A. 2010 Jul 27 ;107(30):13520-5.
de Medina P, Paillasse MR, Segala G, Poirot M, Silvente-Poirot S. Proc Natl Acad Sci U S A. 2010 Jul 27 ;107(30):13520-5.
Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL) : report of the EORTC randomized phase 3 trial 58951.
De Moerloose B, Suciu S, Bertrand Y, Mazingue F, Robert A, Uyttebroeck A, Yakouben K, Ferster A, Margueritte G, Lutz P, Munzer M, Sirvent N, Norton L, Boutard P, Plantaz D, Millot F, Philippet P, Baila L, Benoit Y, Otten J ; Children’s Leukemia Group of the European Organisation for Research and Treatment of Cancer (EORTC). Blood. 2010 Jul 8 ;116(1):36-44.
De Moerloose B, Suciu S, Bertrand Y, Mazingue F, Robert A, Uyttebroeck A, Yakouben K, Ferster A, Margueritte G, Lutz P, Munzer M, Sirvent N, Norton L, Boutard P, Plantaz D, Millot F, Philippet P, Baila L, Benoit Y, Otten J ; Children’s Leukemia Group of the European Organisation for Research and Treatment of Cancer (EORTC). Blood. 2010 Jul 8 ;116(1):36-44.
Bortezomib Plus Dexamethasone Induction Improves Outcome of Patients With t(4 ;14) Myeloma but Not Outcome of Patients With del(17p).
Avet-Loiseau H, Leleu X, Roussel M, Moreau P, Guerin-Charbonnel C, Caillot D, Marit G, Benboubker L, Voillat L, Mathiot C, Kolb B, Macro M, Campion L, Wetterwald M, Stoppa AM, Hulin C, Facon T, Attal M, Minvielle S, Harousseau JL. J Clin Oncol. 2010 Jul 19. PMID : 20644101
Avet-Loiseau H, Leleu X, Roussel M, Moreau P, Guerin-Charbonnel C, Caillot D, Marit G, Benboubker L, Voillat L, Mathiot C, Kolb B, Macro M, Campion L, Wetterwald M, Stoppa AM, Hulin C, Facon T, Attal M, Minvielle S, Harousseau JL. J Clin Oncol. 2010 Jul 19. PMID : 20644101
IgA-mediated human autoimmune hemolytic anemia as a result of hemagglutination in the spleen, but independently of complement activation and FcalphaRI.
Chadebech P, Michel M, Janvier D, Yamada K, Copie-Bergman C, Bodivit G, Bensussan A, Fournie JJ, Godeau B, Bierling P, Izui S, Noizat-Pirenne F. Blood. 2010 Jul 19. PMID : 20644119
Chadebech P, Michel M, Janvier D, Yamada K, Copie-Bergman C, Bodivit G, Bensussan A, Fournie JJ, Godeau B, Bierling P, Izui S, Noizat-Pirenne F. Blood. 2010 Jul 19. PMID : 20644119
A non-ring-like form of the Dam1 complex modulates microtubule dynamics in fission yeast.
Gao Q, Courtheoux T, Gachet Y, Tournier S, He X. Proc Natl Acad Sci U S A. 2010 Jul 27 ;107(30):13330-5.
Gao Q, Courtheoux T, Gachet Y, Tournier S, He X. Proc Natl Acad Sci U S A. 2010 Jul 27 ;107(30):13330-5.
Active site mutations in mammalian DNA Polymerase delta alter accuracy and replication fork progression.
Schmitt MW, Venkatesan RN, Pillaire MJ, Hoffmann JS, Sidorova JM, Loeb LA. J Biol Chem. 2010 Jul 13. PMID : 20628184
Schmitt MW, Venkatesan RN, Pillaire MJ, Hoffmann JS, Sidorova JM, Loeb LA. J Biol Chem. 2010 Jul 13. PMID : 20628184
Association between the herpes simplex virus-1 DNA polymerase and uracil DNA glycosylase.
Bogani F, Corredeira I, Fernandez V, Sattler U, Rutvisuttinunt W, Defais M, Boehmer PE. J Biol Chem. 2010 Jul 2. PMID : 20601642
Bogani F, Corredeira I, Fernandez V, Sattler U, Rutvisuttinunt W, Defais M, Boehmer PE. J Biol Chem. 2010 Jul 2. PMID : 20601642
The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta.
Noguer-Dance M, Abu-Amero S, Al-Khtib M, Lefèvre A, Coullin P, Moore GE, Cavaillé J. Hum Mol Genet. 2010 Jul 19. PMID : 20610438
Noguer-Dance M, Abu-Amero S, Al-Khtib M, Lefèvre A, Coullin P, Moore GE, Cavaillé J. Hum Mol Genet. 2010 Jul 19. PMID : 20610438
Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Wang X, Pankratz VS, Fredericksen Z, Tarrell R, Karaus M, McGuffog L, Pharaoh PD, Ponder BA, Dunning AM, Peock S, Cook M, Oliver C, Frost D ; EMBRACE, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Houdayer C ; GEMO, Hogervorst FB, Hooning MJ, Ligtenberg MJ ; HEBON, Spurdle A, Chenevix-Trench G ; kConFab, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Domchek SM, Nathanson KL, Rebbeck TR, Singer CF, Gschwantler-Kaulich D, Dressler C, Fink A, Szabo CI, Zikan M, Foretova L, Claes K, Thomas G, Hoover RN, Hunter DJ, Chanock SJ, Easton DF, Antoniou AC, Couch FJ. Hum Mol Genet. 2010 Jul 15 ;19(14):2886-97.
Wang X, Pankratz VS, Fredericksen Z, Tarrell R, Karaus M, McGuffog L, Pharaoh PD, Ponder BA, Dunning AM, Peock S, Cook M, Oliver C, Frost D ; EMBRACE, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Houdayer C ; GEMO, Hogervorst FB, Hooning MJ, Ligtenberg MJ ; HEBON, Spurdle A, Chenevix-Trench G ; kConFab, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Domchek SM, Nathanson KL, Rebbeck TR, Singer CF, Gschwantler-Kaulich D, Dressler C, Fink A, Szabo CI, Zikan M, Foretova L, Claes K, Thomas G, Hoover RN, Hunter DJ, Chanock SJ, Easton DF, Antoniou AC, Couch FJ. Hum Mol Genet. 2010 Jul 15 ;19(14):2886-97.
Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen.
Locatelli GA, Pospiech H, Tanguy Le Gac N, van Loon B, Hubscher U, Parkkinen S, Syväoja JE, Villani G. Biochem J. 2010 Jul 14 ;429(3):573-82.
Locatelli GA, Pospiech H, Tanguy Le Gac N, van Loon B, Hubscher U, Parkkinen S, Syväoja JE, Villani G. Biochem J. 2010 Jul 14 ;429(3):573-82.
Influence of the live cell DNA marker DRAQ5 on chromatin-associated processes.
Mari PO, Verbiest V, Sabbioneda S, Gourdin AM, Wijgers N, Dinant C, Lehmann AR, Vermeulen W, Giglia-Mari G. DNA Repair (Amst). 2010 Jul 1 ;9(7):848-55.
Mari PO, Verbiest V, Sabbioneda S, Gourdin AM, Wijgers N, Dinant C, Lehmann AR, Vermeulen W, Giglia-Mari G. DNA Repair (Amst). 2010 Jul 1 ;9(7):848-55.
Preclinical and clinical evidence that 18FDG-PET/CT is a reliable tool for the detection of early molecular responses to erlotinib in head and neck cancer.
Vergez S, Delord JP, Thomas F, Rochaix P, Caselles O, Filleron T, Brillouet S, Canal P, Courbon F, Allal BC. Clin Cancer Res. 2010 Jul 26. PMID : 20660574
Vergez S, Delord JP, Thomas F, Rochaix P, Caselles O, Filleron T, Brillouet S, Canal P, Courbon F, Allal BC. Clin Cancer Res. 2010 Jul 26. PMID : 20660574
Emerging concepts for the treatment of hematological malignancies with therapeutic monoclonal antibodies.
Capietto AH, Keirallah S, Gross E, Dauguet N, Laprévotte E, Jean C, Gertner-Dardenne J, Bezombes C, Quillet-Mary A, Poupot M, Ysebaert L, Laurent G, Fournié JJ. Curr Drug Targets. 2010 Jul ;11(7):790-800.
Capietto AH, Keirallah S, Gross E, Dauguet N, Laprévotte E, Jean C, Gertner-Dardenne J, Bezombes C, Quillet-Mary A, Poupot M, Ysebaert L, Laurent G, Fournié JJ. Curr Drug Targets. 2010 Jul ;11(7):790-800.
Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy : from molecular modeling to in vivo evaluation.
Brillouet S, Dorbes S, Courbon F, Picard C, Delord JP, Benoist E, Poirot M, Mestre-Voegtlé B, Silvente-Poirot S. Bioorg Med Chem. 2010 Jul 15 ;18(14):5400-12.
Brillouet S, Dorbes S, Courbon F, Picard C, Delord JP, Benoist E, Poirot M, Mestre-Voegtlé B, Silvente-Poirot S. Bioorg Med Chem. 2010 Jul 15 ;18(14):5400-12.
Nucleotide variability and translation efficiency of the 5’untranslated region of hepatitis A virus : an update from clinical isolates associated with mild and severe hepatitis.
Mackiewicz V, Cammas A, Desbois D, Marchadier E, Pierredon S, Beaulieux F, Dussaix E, Vagner S, Roque-Afonso AM. J Virol. 2010 Jul 14. PMID : 20631141
Mackiewicz V, Cammas A, Desbois D, Marchadier E, Pierredon S, Beaulieux F, Dussaix E, Vagner S, Roque-Afonso AM. J Virol. 2010 Jul 14. PMID : 20631141
Alternative splicing and breast cancer.
Dutertre M, Vagner S, Auboeuf D.RNA Biol. 2010 Jul 25 ;7(4).
Dutertre M, Vagner S, Auboeuf D.RNA Biol. 2010 Jul 25 ;7(4).
A new recurrent translocation t(11 ;14)(q24 ;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia.
Chapiro E, Russell LJ, Struski S, Cavé H, Radford-Weiss I, Valle VD, Lachenaud J, Brousset P, Bernard OA, Harrison CJ, Nguyen-Khac F. Leukemia. 2010 Jul ;24(7):1362-4.
Chapiro E, Russell LJ, Struski S, Cavé H, Radford-Weiss I, Valle VD, Lachenaud J, Brousset P, Bernard OA, Harrison CJ, Nguyen-Khac F. Leukemia. 2010 Jul ;24(7):1362-4.
Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress : Role in the physiopathology of the disease.
Ousset M, Bouquet F, Fallone F, Biard D, Dray C, Valet P, Salles B, Muller C. Cell Cycle. 2010 Jul 3 ;9(14).
Ousset M, Bouquet F, Fallone F, Biard D, Dray C, Valet P, Salles B, Muller C. Cell Cycle. 2010 Jul 3 ;9(14).
Immune recovery after fludarabine-cyclophosphamide-rituximab treatment in B-chronic lymphocytic leukemia : implication for maintenance immunotherapy.
Ysebaert L, Gross E, Kühlein E, Blanc A, Corre J, Fournié JJ, Laurent G, Quillet-Mary A. Leukemia. 2010 Jul ;24(7):1310-6.
Ysebaert L, Gross E, Kühlein E, Blanc A, Corre J, Fournié JJ, Laurent G, Quillet-Mary A. Leukemia. 2010 Jul ;24(7):1310-6.
The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis.
Hanoun N, Delpu Y, Suriawinata AA, Bournet B, Bureau C, Selves J, Tsongalis GJ, Dufresne M, Buscail L, Cordelier P, Torrisani J. Clin Chem. 2010 Jul ;56(7):1107-18.
Hanoun N, Delpu Y, Suriawinata AA, Bournet B, Bureau C, Selves J, Tsongalis GJ, Dufresne M, Buscail L, Cordelier P, Torrisani J. Clin Chem. 2010 Jul ;56(7):1107-18.
Apolipoprotein E-Deficient Mice Develop an Anti-Chlamydophila pneumoniae T Helper 2 Response and Resist Vascular Infection.
Nazzal D, Therville N, Yacoub-Youssef H, Garcia V, Thomsen M, Levade T, Segui B, Benoist H. J Infect Dis. 2010 Jul 15. PMID : 20632890
Nazzal D, Therville N, Yacoub-Youssef H, Garcia V, Thomsen M, Levade T, Segui B, Benoist H. J Infect Dis. 2010 Jul 15. PMID : 20632890
Farber lipogranulomatosis type 1 - Late presentation and early death in a Croatian boy with a novel homozygous ASAH1 mutation.
Cvitanovic-Sojat L, Juraski RG, Sabourdy F, Fensom AH, Fumic K, Paschke E, Levade T. Eur J Paediatr Neurol. 2010 Jul 5. PMID : 20609603
Cvitanovic-Sojat L, Juraski RG, Sabourdy F, Fensom AH, Fumic K, Paschke E, Levade T. Eur J Paediatr Neurol. 2010 Jul 5. PMID : 20609603
Theoretical Investigation of Hydrogen Atom Transfer in the Cytosine-Guanine Base Pair and Its Coupling with Electronic Rearrangement. Concerted vs Stepwise Mechanism.
Villani G. J Phys Chem B. 2010 Jul 29 ;114(29):9653-62.
Villani G. J Phys Chem B. 2010 Jul 29 ;114(29):9653-62.
Human fibroblasts share immunosuppressive properties with bone marrow mesenchymal stem cells.
Cappellesso-Fleury S, Puissant-Lubrano B, Apoil PA, Titeux M, Winterton P, Casteilla L, Bourin P, Blancher A. J Clin Immunol. 2010 Jul ;30(4):607-19.
Cappellesso-Fleury S, Puissant-Lubrano B, Apoil PA, Titeux M, Winterton P, Casteilla L, Bourin P, Blancher A. J Clin Immunol. 2010 Jul ;30(4):607-19.
Hypervalent Silicon Compounds by Coordination of Diphosphine-Silanes to Gold.
Gualco P, Mercy M, Ladeira S, Coppel Y, Maron L, Amgoune A, Bourissou D. Chemistry. 2010 Jul 30. PMID : 20677199
Gualco P, Mercy M, Ladeira S, Coppel Y, Maron L, Amgoune A, Bourissou D. Chemistry. 2010 Jul 30. PMID : 20677199
Prophylaxis of invasive aspergillosis with voriconazole or caspofungin during building work in patients with acute leukemia.
Chabrol A, Cuzin L, Huguet F, Alvarez M, Verdeil X, Linas MD, Cassaing S, Giron J, Tetu L, Attal M, Récher C. Haematologica. 2010 Jun ;95(6):996-1003.
Chabrol A, Cuzin L, Huguet F, Alvarez M, Verdeil X, Linas MD, Cassaing S, Giron J, Tetu L, Attal M, Récher C. Haematologica. 2010 Jun ;95(6):996-1003.
Vitamin D deficiency does not alter biochemical markers of bone metabolism before or after autograft in patients with multiple myeloma.
Laroche M, Lemaire O, Attal M. Eur J Haematol. 2010 Jul ;85(1):65-7.
Laroche M, Lemaire O, Attal M. Eur J Haematol. 2010 Jul ;85(1):65-7.
Tandem versus single autologous peripheral blood stem cell transplantation as post-remission therapy in adult acute myeloid leukemia patients under 60 in first complete remission : results of the multicenter prospective phase III GOELAMS LAM-2001 trial.
Chevallier P, Fornecker L, Lioure B, Béné MC, Pigneux A, Recher C, Witz B, Fegueux N, Bulabois CE, Daliphard S, Bouscary D, Vey N, Delain M, Bay JO, Turlure P, Bernard M, Himberlin C, Luquet I, Ifrah N, Harousseau JL ; GOELAMS. Leukemia. 2010 Jul ;24(7):1380-5.
Chevallier P, Fornecker L, Lioure B, Béné MC, Pigneux A, Recher C, Witz B, Fegueux N, Bulabois CE, Daliphard S, Bouscary D, Vey N, Delain M, Bay JO, Turlure P, Bernard M, Himberlin C, Luquet I, Ifrah N, Harousseau JL ; GOELAMS. Leukemia. 2010 Jul ;24(7):1380-5.
Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma.
Lode’ L, Eveillard M, Trichet V, Soussi T, Wuilleme S, Richebourg S, Magrangeas F, Ifrah N, Campion L, Traulle C, Guilhot F, Caillot D, Marit G, Mathiot C, Facon T, Attal M, Harousseau JL, Moreau P, Minvielle S, Avet-Loiseau H. Haematologica. 2010 Jul 15. PMID : 20634494
Lode’ L, Eveillard M, Trichet V, Soussi T, Wuilleme S, Richebourg S, Magrangeas F, Ifrah N, Campion L, Traulle C, Guilhot F, Caillot D, Marit G, Mathiot C, Facon T, Attal M, Harousseau JL, Moreau P, Minvielle S, Avet-Loiseau H. Haematologica. 2010 Jul 15. PMID : 20634494
TNF-alpha induced PMN apoptosis in whole human blood : Protective effect of SSR180575, a potent and selective peripheral benzodiazepine ligand.
Leducq-Alet N, Vin V, Savi P, Bono F. Biochem Biophys Res Commun. 2010 Jul 16. PMID : 20621066
Leducq-Alet N, Vin V, Savi P, Bono F. Biochem Biophys Res Commun. 2010 Jul 16. PMID : 20621066
Coregistration of Prechemotherapy PET-CT for Planning Pediatric Hodgkin’s Disease Radiotherapy Significantly Diminishes Interobserver Variability of Clinical Target Volume Definition.
Metwally H, Courbon F, David I, Filleron T, Blouet A, Rives M, Izar F, Zerdoud S, Plat G, Vial J, Robert A, Laprie A. Int J Radiat Oncol Biol Phys. 2010 Jul 7. PMID : 20615626
Metwally H, Courbon F, David I, Filleron T, Blouet A, Rives M, Izar F, Zerdoud S, Plat G, Vial J, Robert A, Laprie A. Int J Radiat Oncol Biol Phys. 2010 Jul 7. PMID : 20615626
Incidence of micrometastases in histologically negative para-aortic lymph nodes in advanced cervical cancer patients.
Martínez A, Mery E, Ferron G, Querleu D. Gynecol Oncol. 2010 Jul 26. PMID : 20667586
Martínez A, Mery E, Ferron G, Querleu D. Gynecol Oncol. 2010 Jul 26. PMID : 20667586
Recurrence during pregnancy of a conservatively treated early-stage cervical squamous cell carcinoma.
Jadoul P, Querleu D, Squifflet JL, Donnez J. Fertil Steril. 2010 Jul 22. PMID : 20655526
Jadoul P, Querleu D, Squifflet JL, Donnez J. Fertil Steril. 2010 Jul 22. PMID : 20655526
Chronic hepatitis E virus infection : successful virologic response to pegylated interferon-alpha therapy.
Alric L, Bonnet D, Laurent G, Kamar N, Izopet J. Ann Intern Med. 2010 Jul 20 ;153(2):135-6.
Alric L, Bonnet D, Laurent G, Kamar N, Izopet J. Ann Intern Med. 2010 Jul 20 ;153(2):135-6.
Efficacy of synthetic glue treatment of high crypoglandular fistula-in-ano.
Queralto M, Portier G, Bonnaud G, Chotard JP, Cabarrot P, Lazorthes F. Gastroenterol Clin Biol. 2010 Jul 29. PMID : 20674201
Queralto M, Portier G, Bonnaud G, Chotard JP, Cabarrot P, Lazorthes F. Gastroenterol Clin Biol. 2010 Jul 29. PMID : 20674201
French clinical practice guidelines on the management of patients on vitamin K antagonists in at-risk situations (overdose, risk of bleeding, and active bleeding).
Pernod G, Godiér A, Gozalo C, Tremey B, Sié P ; for the working group members. Thromb Res. 2010 Jul 13. PMID : 20630568
Pernod G, Godiér A, Gozalo C, Tremey B, Sié P ; for the working group members. Thromb Res. 2010 Jul 13. PMID : 20630568
Publié le 03-08-2010