Publications de nos équipes - décembre 2011

A switch of GPCR binding preference from PI3K-p85 to filamin-A negatively controls the PI3K pathway.
Najib S, Saint-Laurent N, Estève JP, Schulz S, Boutet-Robinet E, Fourmy D, Lättig J, Mollereau C, Pyronnet S, Susini C, Bousquet C. Mol Cell Biol. 2011 Dec 27. PMID : 22203038.

 

Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals.
Mavigner M, Cazabat M, Dubois M, L’faqihi FE, Requena M, Pasquier C, Klopp P, Amar J, Alric L, Barange K, Vinel JP, Marchou B, Massip P, Izopet J, Delobel P. J Clin Invest. 2011 Dec 12. pii : 59011. doi : 10.1172/JCI59011. PMID : 22156200

Prognostic Impact of Morphologic and Phenotypic Features of Childhood ALK-Positive Anaplastic Large-Cell Lymphoma : Results of the ALCL99 Study.
Lamant L, McCarthy K, d’Amore E, Klapper W, Nakagawa A, Fraga M, Maldyk J, Simonitsch-Klupp I, Oschlies I, Delsol G, Mauguen A, Brugières L, Le Deley MC. J Clin Oncol. 2011 Dec 10 ;29(35):4669-76.

 

A phase 3 trial of bevacizumab in ovarian cancer.
Perren TJ, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Kurzeder C, du Bois A, Sehouli J, Kimmig R, Stähle A, Collinson F, Essapen S, Gourley C, Lortholary A, Selle F, Mirza MR, Leminen A, Plante M, Stark D, Qian W, Parmar MK, Oza AM ; ICON7 Investigators. N Engl J Med. 2011 Dec 29 ;365(26):2484-96.

 

Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2) : a randomised, placebo-controlled, phase 3 study.
Pavel ME, Hainsworth JD, Baudin E, Peeters M, Hörsch D, Winkler RE, Klimovsky J, Lebwohl D, Jehl V, Wolin EM, Oberg K, Van Cutsem E, Yao JC ; RADIANT-2 Study Group. Lancet. 2011 Dec 10 ;378(9808):2005-12.

 

Mammalian Ino80 Mediates Double-Strand Break Repair through Its Role in DNA End Strand Resection.
Gospodinov A, Vaissiere T, Krastev DB, Legube G, Anachkova B, Herceg Z. Mol Cell Biol. 2011 Dec ;31(23):4735-45.

 

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers.
de Saint-Jean M, Delfosse V, Douguet D, Chicanne G, Payrastre B, Bourguet W, Antonny B, Drin G. J Cell Biol. 2011 Dec 12 ;195(6):965-78.

 

Sequence-Specific Base Pair Mimics Are Efficient Topoisomerase IB Inhibitors.
Vekhoff P, Duca M, Guianvarc’h D, Benhida R, Arimondo PB. Biochemistry. 2011 Dec 23. PMID : 22124209

 

p27(Kip1) represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.
Pippa R, Espinosa L, Gundem G, García-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, López-Bigas N, Paramio JM, Bigas A, Bachs O. Oncogene. 2011 Dec 19. doi : 10.1038/onc.2011.582. PMID : 22179826

 

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks.
Cheng Q, Barboule N, Frit P, Gomez D, Bombarde O, Couderc B, Ren GS, Salles B, Calsou P. Nucleic Acids Res. 2011 Dec 1 ;39(22):9605-19.

 

Copy number variation analysis of matched ovarian primary tumors and peritoneal metastasis.
Malek JA, Mery E, Mahmoud YA, Al-Azwani EK, Roger L, Huang R, Jouve E, Lis R, Thiery JP, Querleu D, Rafii A. PLoS One. 2011 ;6(12):e28561. Epub 2011 Dec 14. PMID : 22194851

 

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.
Cox DG, Simard J, Sinnett D, Hamdi Y, Soucy P, Ouimet M, Barjhoux L, Verny-Pierre C, McGuffog L, Healey S, Szabo C, Greene MH, Mai PL, Andrulis IL ; Ontario Cancer Genetics Network, Thomassen M, Gerdes AM, Caligo MA, Friedman E, Laitman Y, Kaufman B, Paluch SS, Borg Å, Karlsson P, Askmalm MS, Bustinza GB ; SWE-BRCA Collaborators, Nathanson KL, Domchek SM, Rebbeck TR, Benítez J, Hamann U, Rookus MA, van den Ouweland AM, Ausems MG, Aalfs CM, van Asperen CJ, Devilee P, Gille HJ ; HEBON ; EMBRACE, Peock S, Frost D, Evans DG, Eeles R, Izatt L, Adlard J, Paterson J, Eason J, Godwin AK, Remon MA, Moncoutier V, Gauthier-Villars M, Lasset C, Giraud S, Hardouin A, Berthet P, Sobol H, Eisinger F, Bressac de Paillerets B, Caron O, Delnatte C ; GEMO Study Collaborators, Goldgar D, Miron A, Ozcelik H, Buys S, Southey MC, Terry MB ; Breast Cancer Family Registry, Singer CF, Dressler AC, Tea MK, Hansen TV, Johannsson O, Piedmonte M, Rodriguez GC, Basil JB, Blank S, Toland AE, Montagna M, Isaacs C, Blanco I, Gayther SA, Moysich KB, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ditsch N, Arnold N, Niederacher D, Sutter C, Gadzicki D, Fiebig B, Caldes T, Laframboise R, Nevanlinna H, Chen X, Beesley J, Spurdle AB, Neuhausen SL, Ding YC, Couch FJ, Wang X, Peterlongo P, Manoukian S, Bernard L, Radice P, Easton DF, Chenevix-Trench G, Antoniou AC, Stoppa-Lyonnet D, Mazoyer S, Sinilnikova OM ; Consortium of Investigators of Modifiers of BRCA1/2. Hum Mol Genet. 2011 Dec 1 ;20(23):4732-47.

 

Identification of a new stilbene-derived inducer of paraoxonase 1 and ligand of the Aryl hydrocarbon Receptor.
Guyot E, Coumoul X, Chassé JF, Khallouki F, Savouret JF, Poirot M, Barouki R. Biochem Pharmacol. 2011 Dec 16. PMID : 22197899

 

Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II.
Brel V, Annereau JP, Vispé S, Kruczynski A, Bailly C, Guilbaud N. Biochem Pharmacol. 2011 Dec 15 ;82(12):1843-52.

 

Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas.
Dejean E, Renalier MH, Foisseau M, Agirre X, Joseph N, de Paiva GR, Al Saati T, Soulier J, Desjobert C, Lamant L, Prósper F, Felsher DW, Cavaillé J, Prats H, Delsol G, Giuriato S, Meggetto F. Leukemia. 2011 Dec ;25(12):1882-90. doi : 10.1038/leu.2011.168. Epub 2011 Jul 22. PMID : 21778999

 

High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia : a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.
Vergez F, Green AS, Tamburini J, Sarry JE, Gaillard B, Cornillet-Lefebvre P, Pannetier M, Neyret A, Chapuis N, Ifrah N, Dreyfus F, Manenti S, Demur C, Delabesse E, Lacombe C, Mayeux P, Bouscary D, Recher C, Bardet V. Haematologica. 2011 Dec ;96(12):1792-8.

 

UVA-activated synthesis of metalloproteinases 1, 3 and 9 is prevented by a broad-spectrum sunscreen.
Jean C, Bogdanowicz P, Haure MJ, Castex-Rizzi N, Fournié JJ, Laurent G. Photodermatol Photoimmunol Photomed. 2011 Dec ;27(6):318-24. doi : 10.1111/j.1600-0781.2011.00627.x. PMID:22092736

 

Protein phosphatase-2A activation is a critical step for enzastaurin activity in chronic lymphoid leukemia cells.
Liffraud C, Quillet-Mary A, Fournié JJ, Laurent G, Ysebaert L. Leuk Lymphoma. 2011 Dec 6. PMID : 22023517

 

Human adipose-derived stromal cells efficiently support hematopoiesis in vitro and in vivo : a key step for therapeutic studies.
De Toni F, Poglio S, Youcef AB, Cousin B, Pflumio F, Bourin P, Casteilla L, Laharrague P. Stem Cells Dev. 2011 Dec ;20(12):2127-38.

 

Current Scientific Rationale for the Use of Somatostatin Analogs and mTOR Inhibitors in Neuroendocrine Tumor Therapy.
Bousquet C, Lasfargues C, Chalabi M, Moatassim Billah S, Susini C, Vezzosi D, Caron P, Pyronnet S. J Clin Endocrinol Metab. 2011 Dec 14. PMID : 22170729

 

Expression of nitric oxide synthases in primary ciliary dyskinesia.
Degano B, Valmary S, Serrano E, Brousset P, Arnal JF. Hum Pathol. 2011 Dec ;42(12):1855-61.

 

Hydrodynamic manipulation of DNA in nanopost arrays : unhooking dynamics and size separation.
Viero Y, He Q, Bancaud A. Small. 2011 Dec 16 ;7(24):3508-18. doi : 0.1002/smll.201101345. Epub 2011 Oct 21. PMID : 22021039

 

Combinatorial coding of Drosophila muscle shape by Collier and Nautilus.
Enriquez J, de Taffin M, Crozatier M, Vincent A, Dubois L. Dev Biol. 2011 Dec 20. PMID : 22200594

 

Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors.
Beck J, Guminski Y, Long C, Marcourt L, Derguini F, Plisson F, Grondin A, Vandenberghe I, Vispé S, Brel V, Aussagues Y, Ausseil F, Arimondo PB, Massiot G, Sautel F, Cantagrel F. Bioorg Med Chem. 2011 Dec 8. PMID : 22206869

 

(2)H NMR calculations on polynuclear transition metal complexes : on the influence of local symmetry and other factors.
Del Rosal I, Gutmann T, Walaszek B, Gerber IC, Chaudret B, Limbach HH, Buntkowsky G, Poteau R. Phys Chem Chem Phys. 2011 Dec 7 ;13(45):20199-207.

 

Room-Temperature Synthesis of Air-Stable and Size-Tunable Luminescent ZnS-Coated Cd(3) P(2) Nanocrystals with High Quantum Yields.
Ojo WS, Xu S, Delpech F, Nayral C, Chaudret B. Angew Chem Int Ed Engl. 2011 Dec 7. doi : 10.1002/anie.201104864. PMID : 22162334

 

Room-temperature tunnel magnetoresistance in self-assembled chemically synthesized metallic iron nanoparticles.
Dugay J, Tan RP, Meffre A, Blon T, Lacroix LM, Carrey J, Fazzini PF, Lachaize S, Chaudret B, Respaud M. Nano Lett. 2011 Dec 14 ;11(12):5128-34.

 

Ruthenium nanoparticles stabilized by N-heterocyclic carbenes : ligand location and influence on reactivity.
Lara P, Rivada-Wheelaghan O, Conejero S, Poteau R, Philippot K, Chaudret B. Angew Chem Int Ed Engl. 2011 Dec 9 ;50(50):12080-4. doi : 10.1002/anie.201106348. Epub 2011 Oct 28. PMID : 22038786

 

Three-dimensional closed microfluidic channel fabrication by stepper projection single step lithography : the diabolo effect.
Larramendy F, Mazenq L, Temple-Boyer P, Nicu L. Lab Chip. 2011 Dec 14 ;12(2):387-90.

 

Proteasome Inhibitors from Neoboutonia melleri.
Long C, Beck J, Cantagrel F, Marcourt L, Vendier L, David B, Plisson F, Derguini F, Vandenberghe I, Aussagues Y, Ausseil F, Lavaud C, Sautel F, Massiot G. J Nat Prod. 2011 Dec 14. PMID : 22168134

 

Respiratory Gating Techniques for Optimization of Lung Cancer Radiotherapy.
Giraud P, Morvan E, Claude L, Mornex F, Le Pechoux C, Bachaud JM, Boisselier P, Beckendorf V, Morelle M, Carrère MO ; The STIC Study Centers. J Thorac Oncol. 2011 Dec ;6(12):2058-68.

 

Complexation of triptolide and its succinate derivative with cyclodextrins : affinity capillary electrophoresis, isothermal titration calorimetry and 1H NMR studies.
Danel C, Duval C, Azaroual N, Vaccher C, Bonte JP, Bailly C, Landy D, Goossens JF. J Chromatogr A. 2011 Dec 2 ;1218(48):8708-14.

 

Evaluation of cost savings with ferric carboxymaltose in anemia treatment through its impact on erythropoiesis-stimulating agents and blood transfusion : French healthcare payer perspective.
Luporsi E, Mahi L, Morre C, Wernli J, de Pouvourville G, Bugat R. J Med Econ. 2011 Dec 5. PMID : 22077267

 

Tracking of single and multiple genomic loci in living yeast cells.
Lassadi I, Bystricky K. Methods Mol Biol. 2011 ;745:499-522.

 

[Use of adipose tissue in regenerative medicine].
Casteilla L, Planat-Benard V, Bourin P, Laharrague P, Cousin B. Transfus Clin Biol. 2011 Apr ;18(2):124-8.

 

Correlating early evolution of parasitic platyhelminths to Gondwana breakup.
Badets M, Whittington I, Lalubin F, Allienne JF, Maspimby JL, Bentz S, Du Preez LH, Barton D, Hasegawa H, Tandon V, Imkongwapang R, Ohler A, Combes C, Verneau O. Syst Biol. 2011 Dec 1 ;60(6):762-81

 

[Neoadjuvant treatment of breast cancer : Implications for the pathologist].
Le Guellec S, Perallon R, Alunni JP, Charitansky H, Leaha C, Gonzalez AM, Chateau MC, Simony-Lafontaine J, Jacot W, Gutowski M, Penault-Llorca F, Dalenc F, Lacroix-Triki M. Ann Pathol. 2011 Dec ;31(6):442-54.

 

Brachytherapy in lip carcinoma : long-term results.
Guibert M, David I, Vergez S, Rives M, Filleron T, Bonnet J, Delannes M. Int J Radiat Oncol Biol Phys. 2011 Dec 1 ;81(5):e839-43. PMID : 21163589

 

Live cell division dynamics monitoring in 3D large spheroid tumor models using light sheet microscopy.
Lorenzo C, Frongia C, Jorand R, Fehrenbach J, Weiss P, Maandhui A, Gay G, Ducommun B, Lobjois V. Cell Div. 2011 Dec 12 ;6(1):22.

 

Characteristics of lung cancer in women : Importance of hormonal and growth factors.
Rouquette I, Lauwers-Cances V, Allera C, Brouchet L, Milia J, Nicaise Y, Laurent J, Delisle MB, Favre G, Didier A, Mazières J. Lung Cancer. 2011 Dec 22. PMID : 22197614

 

Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives.
Rives A, Baudoin-Dehoux C, Saffon N, Andrieu-Abadie N, Génisson Y. Org Biomol Chem. 2011 Dec 7 ;9(23):8163-70.

 

Variation in breast cancer risk with mutation position, smoking, alcohol, and chest X-ray history, in the French National BRCA1/2 carrier cohort (GENEPSO).
Lecarpentier J, Noguès C, Mouret-Fourme E, Stoppa-Lyonnet D, Lasset C, Caron O, Fricker JP, Gladieff L, Faivre L, Sobol H, Gesta P, Frenay M, Luporsi E, Coupier I ; GENEPSO, Lidereau R, Andrieu N. Breast Cancer Res Treat. 2011 Dec ;130(3):927-38.

 

Electrotransfer of RNAi-based Oligonucleotides for Oncology.
Chabot S, Pelofy S, Paganin-Gioanni A, Teissie J, Golzio M. Anticancer Res. 2011 Dec ;31(12):4083-9.

 

Management of gastrointestinal stromal tumours of limited size : Proposals from a French panel of physicians.
Landi B, Bouché O, Guimbaud R, Aparicio T, Berger A, Bonvalot S, Buecher B, Blay JY, Boustière C, Coindre JM, Emile JF, Giovannini M, Lecomte T, Le Cesne A, Monges G, Napoléon B, Palazzo L, Chayvialle JA. Dig Liver Dis. 2011 Dec ;43(12):935-9.

 

Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice.
Attané C, Foussal C, Le Gonidec S, Benani A, Daviaud D, Wanecq E, Guzmán-Ruiz R, Dray C, Bezaire V, Rancoule C, Kuba K, Ruiz-Gayo M, Levade T, Penninger J, Burcelin R, Pénicaud L, Valet P, Castan-Laurell I. Diabetes. 2011 Dec 30. PMID : 22210322

 

Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacterial agents.
Azéma J, Guidetti B, Korolyov A, Kiss R, Roques C, Constant P, Daffé M, Malet-Martino M. Eur J Med Chem. 2011 Dec ;46(12):6025-38.

 

Thermotropic liquid crystals as templates for anisotropic growth of nanoparticles.
Saliba S, Coppel Y, Achard MF, Mingotaud C, Marty JD, Kahn ML. Angew Chem Int Ed Engl. 2011 Dec 9 ;50(50):12032-5. doi : 10.1002/anie.201105314. Epub 2011 Oct 17. PMID : 22006438

 

RNA-binding proteins, RNA granules, and gametes : is unity strength ?
Nguyen-Chi M, Morello D. Reproduction. 2011 Dec ;142(6):803-17

 

The THEMA study : a sociodemographic survey of hypercholesterolaemic individuals.
Fournier T, Bruckert E, Czernichow S, Paulmyer A, Poulain JP. J Hum Nutr Diet. 2011 Dec ;24(6):572-81. doi : 10.1111/j.1365-277X.2011.01168.x. PMID : 21585569

 

Influence of social factors on weight-related behaviors according to gender in the French adult population.
Pigeyre M, Duhamel A, Poulain JP, Rousseaux J, Barbe P, Jeanneau S, Tibère L, Romon M. Appetite. 2011 Dec 6. PMID : 22178649

 

Current Scientific Rationale for the Use of Somatostatin Analogs and mTOR Inhibitors in Neuroendocrine Tumor Therapy.
Bousquet C, Lasfargues C, Chalabi M, Moatassim Billah S, Susini C, Vezzosi D, Caron P, Pyronnet S. J Clin Endocrinol Metab. 2011 Dec 14. PMID : 22170729

 

Ovarian preservation during treatment of early stage endometrial cancer.
Poilblanc M, Samouelian V, Querleu D. Bull Cancer. 2011 Dec 26. PMID : 22198406

 

Times have really changed !
Canis M, Querleu D, Pomel C. Gynecol Oncol. 2011 Dec 13. PMID : 22173089

 

Age assessment by magnetic resonance imaging of the knee : A preliminary study.
Dedouit F, Auriol J, Rousseau H, Rougé D, Crubézy E, Telmon N. Forensic Sci Int. 2011 Dec 5. PMID : 22153621

 

Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants : Thrombin or factor-Xa inhibitors. Recommendations of the Working Group on perioperative haemostasis and the French Study Group on thrombosis and haemostasis.
Sié P, Samama CM, Godier A, Rosencher N, Steib A, Llau JV, Van der Linden P, Pernod G, Lecompte T, Gouin-Thibault I, Albaladejo P. Arch Cardiovasc Dis. 2011 Dec ;104(12):669-76.

 

Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis : A randomized trial comparing 3- and 6-month periodicities.
Trinchet JC, Chaffaut C, Bourcier V, Degos F, Henrion J, Fontaine H, Roulot D, Mallat A, Hillaire S, Cales P, Ollivier I, Vinel JP, Mathurin P, Bronowicki JP, Vilgrain V, N’kontchou G, Beaugrand M, Chevret S ; for the Groupe d’Etude et de Traitement du Carcinome Hépatocellulaire (GRETCH). Hepatology. 2011 Dec ;54(6):1987-1997. doi : 10.1002/hep.24545. PMID : 22144108

 

Influence of Sildenafil on Micturition and Urethral Tone in Ovariectomized and Non-ovariectomized Mice.
Gamé X, Bouali O, Allard J, Gourdy P, Escourrou G, Tack I, Rischmann P, Arnal JF, Malavaud B. J Sex Med. 2011 Dec 6. doi : 10.1111/j.1743-6109.2011.02559.x. PMID : 22145776

 

[Fertility after prostate brachytherapy with Iode 125 permanent implants for localized prostate cancer].
Delaunay B, Delannes M, Bachaud JM, Bouaziz M, Salloum A, Thoulouzan M, Soulié M, Plante P, Huyghe E. Prog Urol. 2012 Jan ;22(1):53-7. French. PMID : 22196006

 

[Pelvic exenteration : State-of-the-art and perspectives.]
Ferron G, Pomel C, Martinez A, Narducci F, Lambaudie E, Marchal F, Rouanet P, Querleu D. Gynecol Obstet Fertil. 2011 Dec 20. [Epub ahead of print] French. PMID : 22192690

 

[Quality control of the surgical management of advanced ovarian carcinoma.]
Pomel C, Lecuru F, Rouzier R, Dauplat J, Ferron G. J Gynecol Obstet Biol Reprod (Paris). 2011 Dec 20. French. PMID : 22192233