Actualités


Publications de nos équipes - avril 2012

Long-Term Analysis of the IFM 99 Trials for Myeloma : Cytogenetic Abnormalities [t(4 ;14), del(17p), 1q gains] Play...
Publié le 10-05-2012
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Publications de nos équipes - Mars 2012

p27Kip1 controls cytokinesis via the regulation of citron kinase activation. Serres MP, Kossatz U, Chi Y, Roberts...
Publié le 03-04-2012
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Pole de recherche hospitalo-universitaire CAPTOR

Le projet CAPTOR (Cancer Pharmacology of Toulouse and Region ) a été labellisé par l’ANR , dans le cadre des...
Publié le 22-03-2012
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Publications de nos équipes - Février 2012

Size control of the Drosophila hematopoietic niche by bone morphogenetic protein signaling reveals parallels with...
Publié le 05-03-2012
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Labex Toucan

Le projet Toucan a été labellisé dans le cadre de l’appel d’offre Labex (Laboratoire d’excellence). Félicitations au...
Publié le 22-02-2012
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Les équipes > Actualités équipes

Publications de nos équipes - novembre 2011

Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules.
Moussion C, Girard JP. Nature. 2011 Nov 13 ;479(7374):542-6. doi : 10.1038/nature10540. PMID : 22080953
 
Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes.
Egloff S, Zaborowska J, Laitem C, Kiss T, Murphy S. Mol Cell. 2011 Nov 30. PMID : 22137580
 
Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B) : an open-label randomised phase 3 trial.
Récher C, Coiffier B, Haioun C, Molina TJ, Fermé C, Casasnovas O, Thiéblemont C, Bosly A, Laurent G, Morschhauser F, Ghesquières H, Jardin F, Bologna S, Fruchart C, Corront B, Gabarre J, Bonnet C, Janvier M, Canioni D, Jais JP, Salles G, Tilly H ; Groupe d’Etude des Lymphomes de l’Adulte. Lancet. 2011 Nov 26 ;378(9806):1858-67.
 
Prognostic Impact of Morphologic and Phenotypic Features of Childhood ALK-Positive Anaplastic Large-Cell Lymphoma : Results of the ALCL99 Study.
Lamant L, McCarthy K, d’Amore E, Klapper W, Nakagawa A, Fraga M, Maldyk J, Simonitsch-Klupp I, Oschlies I, Delsol G, Mauguen A, Brugières L, Le Deley MC.
J Clin Oncol. 2011 Nov 14. PMID : 22084369
 
The cell cycle regulator CDC25A is a target for JAK2V617F oncogene.
Gautier EF, Picard M, Laurent C, Marty C, Villeval JL, Demur C, Delhommeau F, Hexner E, Giraudier S, Bonnevialle N, Ducommun B, Récher C, Laurent G, Manenti S, Mansat-De Mas V. Blood. 2011 Nov 7. PMID : 22065597
 
Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma : a 3-D tissue-imaging study.
Laurent C, Müller S, Do C, Al-Saati T, Allart S, Larocca LM, Hohaus S, Duchez S, Quillet-Mary A, Laurent G, Brousset P, Valitutti S. Blood. 2011 Nov 17 ;118(20):5371-9.
 
CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.
Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P. Proc Natl Acad Sci U S A. 2011 Nov 22 ;108(47):19072-7.
 
Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma.
Moreau P, Avet-Loiseau H, Facon T, Attal M, Tiab M, Hulin C, Doyen C, Garderet L, Randriamalala E, Araujo C, Lepeu G, Marit G, Caillot D, Escoffre M, Lioure B, Benboubker L, Pégourié B, Kolb B, Stoppa AM, Fuzibet JG, Decaux O, Dib M, Berthou C, Chaleteix C, Sebban C, Traullé C, Fontan J, Wetterwald M, Lenain P, Mathiot C, Harousseau JL. Blood. 2011 Nov 24 ;118(22):5752-8.
 
Sequence-specific base pair mimics are efficient topoisomerase IB inhibitors.
Vekhoff P, Duca M, Guianvarc’h D, Benhida R, Arimondo PB. Biochemistry. 2011 Nov 29. PMID : 22124209
 
The cell cycle regulator CDC25A is a target for JAK2V617F oncogene.
Gautier EF, Picard M, Laurent C, Marty C, Villeval JL, Demur C, Delhommeau F, Hexner E, Giraudier S, Bonnevialle N, Ducommun B, Récher C, Laurent G, Manenti S, Mansat-De Mas V. Blood. 2011 Nov 7. PMID : 22065597
 
Direct effect of rituximab in B-cell-derived lymphoid neoplasias : mechanism, regulation, and perspectives.
Bezombes C, Fournié JJ, Laurent G. Mol Cancer Res. 2011 Nov ;9(11):1435-42.
 
HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis.
Glorian V, Maillot G, Polès S, Iacovoni JS, Favre G, Vagner S. Cell Death Differ. 2011 Nov ;18(11):1692-701. doi : 10.1038/cdd.2011.35.
 
Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers.
Im KM, Kirchhoff T, Wang X, Green T, Chow CY, Vijai J, Korn J, Gaudet MM, Fredericksen Z, Shane Pankratz V, Guiducci C, Crenshaw A, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Mai PL, Greene MH, Piedmonte M, Rubinstein WS ; HEBON, Hogervorst FB, Rookus MA, Collée JM, Hoogerbrugge N, van Asperen CJ, Meijers-Heijboer HE, Van Roozendaal CE, Caldes T, Perez-Segura P, Jakubowska A, Lubinski J, Huzarski T, Blecharz P, Nevanlinna H, Aittomäki K, Lazaro C, Blanco I, Barkardottir RB, Montagna M, D’Andrea E ; kConFab, Devilee P, Olopade OI, Neuhausen SL, Peissel B, Bonanni B, Peterlongo P, Singer CF, Rennert G, Lejbkowicz F, Andrulis IL, Glendon G, Ozcelik H ; Ontario Cancer Genetics Network, Toland AE, Caligo MA ; SWE-BRCA, Beattie MS, Chan S ; UKFOCR, Domchek SM, Nathanson KL, Rebbeck TR, Phelan C, Narod S, John EM, Hopper JL, Buys SS, Daly MB, Southey MC, Terry MB, Tung N, Hansen TV, Osorio A, Benitez J, Durán M, Weitzel JN, Garber J, Hamann U ; EMBRACE, Peock S, Cook M, Oliver CT, Frost D, Platte R, Evans DG, Eeles R, Izatt L, Paterson J, Brewer C, Hodgson S, Morrison PJ, Porteous M, Walker L, Rogers MT, Side LE, Godwin AK, Schmutzler RK, Wappenschmidt B, Laitman Y, Meindl A, Deissler H, Varon-Mateeva R, Preisler-Adams S, Kast K, Venat-Bouvet L, Stoppa-Lyonnet D, Chenevix-Trench G, Easton DF, Klein RJ, Daly MJ, Friedman E, Dean M, Clark AG, Altshuler DM, Antoniou AC, Couch FJ, Offit K, Gold B. Hum Genet. 2011 Nov ;130(5):685-99.
 
Stepwise Maturation of Lytic Granules during Differentiation and Activation of Human CD8 T Lymphocytes.
Sanchez-Ruiz Y, Valitutti S, Dupre L. PLoS One. 2011 ;6(11):e27057. Epub 2011 Nov 4. PMID : 22073254 Free PMC Article
 
Retrospective analysis of local control and cosmetic outcome of 147 periorificial carcinomas of the face treated with low-dose rate interstitial brachytherapy.
Ducassou A, David I, Filleron T, Rives M, Bonnet J, Delannes M. Int J Radiat Oncol Biol Phys. 2011 Nov 1 ;81(3):726-31. 
 
Comparison of doxorubicin and weekly paclitaxel efficacy in metastatic angiosarcomas.
Italiano A, Cioffi A, Penel N, Levra MG, Delcambre C, Kalbacher E, Chevreau C, Bertucci F, Isambert N, Blay JY, Bui B, Antonescu C, D’Adamo DR, Maki RG, Keohan ML. Cancer. 2011 Nov 1. doi : 10.1002/cncr.26599. PMID : 22045619
 
Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer : results of a phase I dose escalation trial.
Melichar B, Casado E, Bridgewater J, Bennouna J, Campone M, Vitek P, Delord JP, Cerman J Jr, Salazar R, Dvorak J, Sguotti C, Urban P, Viraswami-Appanna K, Tan E, Tabernero J. Br J Cancer. 2011 Nov 22 ;105(11):1646-53. doi : 10.1038/bjc.2011.438.
 
Critical features of FAK-expressing AML bone marrow microenvironment through leukemia stem cell hijacking of mesenchymal stromal cells.
Despeaux M, Labat E, Gadelorge M, Prade N, Bertrand J, Demur C, Recher C, Bonnevialle P, Payrastre B, Bourin P, Racaud-Sultan C. Leukemia. 2011 Nov ;25(11):1789-93. doi : 10.1038/leu.2011.145.
 
Unexpected High Levels of Vorinostat when Combined with Vinorelbine in Patients with advanced Cancer.
Gandia1 P, Arellano C, du Rieu CQ, Lochon I, Campone M, Pierga JY, Poublanc M, Hennebelle I, Filleron T, Chatelut E, Delord JP. Curr Clin Pharmacol. 2011 Nov 11. PMID : 22082325
 
Room-Temperature Tunnel Magnetoresistance in Self-Assembled Chemically Synthesized Metallic Iron Nanoparticles.
Dugay J, Tan RP, Meffre A, Blon T, Lacroix LM, Carrey J, Fazzini PF, Lachaize S, Chaudret B, Respaud M. Nano Lett. 2011 Nov 18. PMID : 22098424
 
Size-controllable APTS stabilized ruthenium(0) nanoparticles catalyst for the dehydrogenation of dimethylamine-borane at room temperature.
Zahmakıran M, Philippot K, Ozkar S, Chaudret B. Dalton Trans. 2011 Nov 3. PMID : 22052298
 
Reciprocal polarization of T and B cells at the immunological synapse.
Duchez S, Rodrigues M, Bertrand F, Valitutti S. Immunol. 2011 Nov 1 ;187(9):4571-80.
 
Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease : a prospective study.
Robic MA, Procopet B, Métivier S, Péron JM, Selves J, Vinel JP, Bureau C. J Hepatol. 2011 Nov ;55(5):1017-24.
 
DNA-Polymer Micelles as Nanoparticles with Recognition Ability.
Talom RM, Fuks G, Kaps L, Oberdisse J, Cerclier C, Gaillard C, Mingotaud C, Gauffre F. Chemistry. 2011 Nov 25 ;17(48):13495-501. doi : 10.1002/chem.201101561.
 
Three-dimensional closed microfluidic channel fabrication by stepper projection single step lithography : the diabolo effect.
Larramendy F, Mazenq L, Temple-Boyer P, Nicu L. Lab Chip. 2011 Nov 8. PMID : 22069055
 
Critical features of FAK-expressing AML bone marrow microenvironment through leukemia stem cell hijacking of mesenchymal stromal cells.
Despeaux M, Labat E, Gadelorge M, Prade N, Bertrand J, Demur C, Recher C, Bonnevialle P, Payrastre B, Bourin P, Racaud-Sultan C. Leukemia. 2011 Nov ;25(11):1789-93. doi : 10.1038/leu.2011.145.
 
Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer.
Brugger W, Triller N, Blasinska-Morawiec M, Curescu S, Sakalauskas R, Manikhas GM, Mazieres J, Whittom R, Ward C, Mayne K, Trunzer K, Cappuzzo F. Clin Oncol. 2011 Nov 1 ;29(31):4113-20.
 
Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II.
Ballot C, Jendoubi M, Kluza J, Jonneaux A, Laine W, Formstecher P, Bailly C, Marchetti P. Apoptosis. 2011 Nov 30. PMID : 22127645
 
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents.
Menendez C, Gau S, Lherbet C, Rodriguez F, Inard C, Pasca MR, Baltas M. Eur J Med Chem. 2011 Nov ;46(11):5524-31.
 
In situ mantle cell lymphoma : clinical implications of an incidental finding with indolent clinical behavior.
Carvajal-Cuenca A, Sua LF, Silva NM, Pittaluga S, Royo C, Song JY, Sargent RL, Espinet B, Climent F, Jacobs SA, Delabie J, Naresh KN, Bagg A, Brousset P, Warnke RA, Serrano S, Harris NL, Swerdlow SH, Jaffe ES, Campo E. Haematologica. 2011 Nov 4. PMID : 22058203
 
French brain tumor database : 5-year histological results on 25 756 cases.
Rigau V, Zouaoui S, Mathieu-Daudé H, Darlix A, Maran A, Trétarre B, Bessaoud F, Bauchet F, Attaoua R, Fabbro-Peray P, Fabbro M, Kerr C, Taillandier L, Duffau H, Figarella-Branger D, Costes V, Bauchet L ; Société Française de Neuropathologie (SFNP), Société Française de Neurochirurgie (SFNC) ; Club de Neuro-Oncologie of the Société Française de Neurochirurgie (CNO-SFNC) ; Association des Neuro-Oncologues d’Expression Française (ANOCEF). Brain Pathol. 2011 Nov ;21(6):633-44. doi : 10.1111/j.1750-3639.2011.00491.x.
 
Control of mitochondrial volume by mitochondrial metabolic water.
Casteilla L, Devin A, Carriere A, Salin B, Schaeffer J, Rigoulet M. Mitochondrion. 2011 Nov ;11(6):862-6.
 
Persistent lipid abnormalities in statin-treated patients with diabetes mellitus in Europe and Canada : results of the Dyslipidaemia International Study.
Leiter LA, Lundman P, da Silva PM, Drexel H, Jünger C, Gitt AK ; DYSIS investigators. Diabet Med. 2011 Nov ;28(11):1343-51. doi : 10.1111/j.1464-5491.2011.03360.x. PMID : 21679231
 
A computational chemist approach to gas sensors : Modeling the response of SnO(2) to CO, O(2) , and H(2) O Gases.
Ducéré JM, Hemeryck A, Estève A, Rouhani MD, Landa G, Ménini P, Tropis C, Maisonnat A, Fau P, Chaudret B. J Comput Chem. 2011 Nov 21. doi : 10.1002/jcc.21959. PMID : 22102259
 
Pharmacokinetics and impaired organic functions.
Chatelut E. Bull Cancer. 2011 Nov 1 ;98(11):1347-54.
 
Pharmacology of platinum compounds : differences between the three molecules and factors of interpatient variability.
Chatelut E. Bull Cancer. 2011 Nov 1 ;98(11):1253-61.
 
Strontium-loaded mineral bone cements as sustained release systems : Compositions, release properties, and effects on human osteoprogenitor cells.
Tadier S, Bareille R, Siadous R, Marsan O, Charvillat C, Cazalbou S, Amédée J, Rey C, Combes C. J Biomed Mater Res B Appl Biomater. 2011 Nov 21. doi : 10.1002/jbm.b.31959. PMID : 22102621
 
Cogrinding significance for calcium carbonate-calcium phosphate mixed cement. II. Effect on cement properties.
Tadier S, Bolay NL, Fullana SG, Cazalbou S, Charvillat C, Labarrère M, Boitel D, Rey C, Combes C. J Biomed Mater Res B Appl Biomater. 2011 Nov ;99(2):302-12. doi : 10.1002/jbm.b.31899.
 
Transparency in the presentation of trial results may not increase patients’ trust in medical researchers.
Mancini J, Genre D, Dalenc F, Maylevin F, Martin AL, Viens P, Julian-Reynier C. Clin Trials. 2011 Nov 2. PMID : 22049088
 
Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin ? A single center experience.
Larochelle O, Bertoli S, Vergez F, Sarry JE, Mansat-De Mas V, Dobbelstein S, Dastugue N, Strzelecki AC, Cavelier C, Creancier L, Pillon A, Kruczynski A, Demur C, Sarry A, Huguet F, Huynh A, Récher C, Delabesse E. Oncotarget. 2011 Nov 9. PMID : 22081665
 
Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives.
Rives A, Baudoin-Dehoux C, Saffon N, Andrieu-Abadie N, Génisson Y. Org Biomol Chem. 2011 Nov 10 ;(23):8163-70.
 
Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers : the LIBER trial.
Pujol P, Lasset C, Berthet P, Dugast C, Delaloge S, Fricker JP, Tennevet I, Chabbert-Buffet N, This P, Baudry K, Lemonnier J, Roca L, Mijonnet S, Gesta P, Chiesa J, Dreyfus H, Vennin P, Delnatte C, Bignon YJ, Lortholary A, Prieur F, Gladieff L, Lesur A, Clough KB, Nogues C, Martin AL ; On behalf the French Federation of Cancer Centres (FNCLCC). Fam Cancer. 2011 Nov 11. PMID : 22076253
 
Prospective study of the impact on quality of life of cystectomy with ileal conduit urinary diversion for neurogenic bladder dysfunction.
Guillotreau J, Castel-Lacanal E, Roumiguié M, Bordier B, Doumerc N, De Boissezon X, Malavaud B, Marque P, Rischmann P, Gamé X. Neurourol Urodyn. 2011 Nov ;30(8):1503-6. doi : 10.1002/nau.21121.
 
Multicenter observational study of erlotinib therapy (OBSTAR) for non small-cell lung cancer : a GFPC study.
Vergnenègre A, Monnet I, Chouaïd C, Hureaux J, Mazières J, Quéré G, Lombard JN, Cumin I, Abdiche S, Ejnaini CN, Bonnabau H, Decroisette Ch ; GFPC team. Lung Cancer. 2011 Nov ;74(2):264-7.
 
Prognostic significance of low volume sentinel lymph node disease in early-stage cervical cancer.
Cibula D, Abu-Rustum NR, Dusek L, Zikán M, Zaal A, Sevcik L, Kenter GG, Querleu D, Jach R, Bats AS, Dyduch G, Graf P, Klat J, Lacheta J, Meijer CJ, Mery E, Verheijen R, Zweemer RP. Gynecol Oncol. 2011 Nov 23. PMID : 2120175
 
Anti-p200 pemphigoid : A spectacular response to dapsone.
Munsch C, Prey S, Joly P, Meyer N, Lamant L, Livideanu C, Viraben R, Paul C. Ann Dermatol Venereol. 2011 Nov ;138(11):739-42..
 
Diagnostic value of intraoperative examination of sentinel lymph node in early cervical cancer : a prospective, multicenter study.
Bats AS, Buénerd A, Querleu D, Leblanc E, Daraï E, Morice P, Marret H, Gillaizeau F, Mathevet P, Lécuru F ; SENTICOL collaborative group. Gynecol Oncol. 2011 Nov ;123(2):230-5
 
Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease : a prospective study.
Robic MA, Procopet B, Métivier S, Péron JM, Selves J, Vinel JP, Bureau C. J Hepatol. 2011 Nov ;55(5):1017-24.
 
Direct Involvement of the Acetato Ligand in the Reductive Elimination Step of Rhodium-Catalyzed Methanol Carbonylation.
Lassauque N, Davin T, Nguyen DH, Adcock RJ, Coppel Y, Le Berre C, Serp P, Maron L, Kalck P. Inorg Chem. 2011 Nov 28. PMID : 22122231

Publié le 12-12-2011